Walport, Louise J : rechercher sur Z-Library

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1

Epigenetic regulation by histone demethylases in hypoxia

Hancock, Rebecca L, Dunne, Kate, Walport, Louise J, Flashman, Emily, Kawamura, Akane

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 2.67 MB

english, 2015

2

Protein Chemistry Looking Ahead: 8th Chemical Protein Synthesis Meeting 16-19 June 2019, Berlin, Germany

Bello, Claudia, Hartrampf, Nina, Walport, Louise J., Conibear, Anne C.

Journal:

Cell Chemical Biology

Année:

2019

Langue:

english

Fichier:

PDF, 1.72 MB

english, 2019

3

Linking of 2-Oxoglutarate and Substrate Binding Sites Enables Potent and Highly Selective Inhibition of JmjC Histone Demethylases

Dr. Esther C. Y. Woon, Dr. Anthony Tumber, Dr. Akane Kawamura, Dr. Lars Hillringhaus, Dr. Wei Ge, Dr. Nathan R. Rose, Jerome H. Y. Ma, Mun Chiang Chan, Louise J. Walport, Ka Hing Che, Dr. Stanley S. N

Journal:

Angewandte Chemie International Edition

Année:

2012

Langue:

english

Fichier:

PDF, 2.16 MB

english, 2012

4

Linking of 2-Oxoglutarate and Substrate Binding Sites Enables Potent and Highly Selective Inhibition of JmjC Histone Demethylases

Dr. Esther C. Y. Woon, Dr. Anthony Tumber, Dr. Akane Kawamura, Dr. Lars Hillringhaus, Dr. Wei Ge, Dr. Nathan R. Rose, Jerome H. Y. Ma, Mun Chiang Chan, Louise J. Walport, Ka Hing Che, Dr. Stanley S. N

Journal:

Angewandte Chemie

Année:

2012

Langue:

english

Fichier:

PDF, 2.16 MB

english, 2012

5

Plant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone Demethylases

Rose, Nathan R., Woon, Esther C. Y., Tumber, Anthony, Walport, Louise J., Chowdhury, Rasheduzzaman, Li, Xuan Shirley, King, Oliver N. F., Lejeune, Clarisse, Ng, Stanley S., Krojer, Tobias, Chan, Mun C

Journal:

Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 3.07 MB

english, 2012

6

Mechanisms of human histone and nucleic acid demethylases

Walport, Louise J, Hopkinson, Richard J, Schofield, Christopher J

Journal:

Current Opinion in Chemical Biology

Année:

2012

Langue:

english

Fichier:

PDF, 925 KB

english, 2012

7

The Ugi four-component reaction enables expedient synthesis and comparison of photoaffinity probes

Bush, Jacob T., Walport, Louise J., McGouran, Joanna F., Leung, Ivanhoe K. H., Berridge, Georgina, van Berkel, Sander S., Basak, Amit, Kessler, Benedikt M., Schofield, Christopher J.

Journal:

Chemical Science

Année:

2013

Langue:

english

Fichier:

PDF, 998 KB

english, 2013

8

Dynamic Combinatorial Mass Spectrometry Leads to Inhibitors of a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase

Woon, Esther C. Y., Demetriades, Marina, Bagg, Eleanor A. L., Aik, WeiShen, Krylova, Svetlana M., Ma, Jerome H. Y., Chan, MunChiang, Walport, Louise J., Wegman, David W., Dack, Kevin N., McDonough, Mi

Journal:

Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 4.12 MB

english, 2012

9

Total Synthesis of the Antitumor Antibiotic (±)-Streptonigrin: First- and Second-Generation Routes for de Novo Pyridine Formation Using Ring-Closing Metathesis

Donohoe, Timothy J., Jones, Christopher R., Kornahrens, Anne F., Barbosa, Luiz C. A., Walport, Louise J., Tatton, Matthew R., O’Hagan, Michael, Rathi, Akshat H., Baker, David B.

Journal:

Journal of Organic Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 1.78 MB

english, 2013

10

Identification of the KDM2/7 Histone Lysine Demethylase Subfamily Inhibitor and its Antiproliferative Activity

Suzuki, Takayoshi, Ozasa, Hiroki, Itoh, Yukihiro, Zhan, Peng, Sawada, Hideyuki, Mino, Koshiki, Walport, Louise, Ohkubo, Rei, Kawamura, Akane, Yonezawa, Masato, Tsukada, Yuichi, Tumber, Anthony, Nakaga

Journal:

Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 3.74 MB

english, 2013

11

1H,13C, and15N resonance assignments for the tandem PHD finger motifs of human CHD4

Walport, Louise J., Morra, Rosa, Mancini, Erika J., Redfield, Christina

Journal:

Biomolecular NMR Assignments

Année:

2015

Langue:

english

Fichier:

PDF, 300 KB

english, 2015

12

Studies on the catalytic domains of multiple JmjC oxygenases using peptide substrates

Williams, Sophie T, Walport, Louise J, Hopkinson, Richard J, Madden, Sarah K, Chowdhury, Rasheduzzaman, Schofield, Christopher J, Kawamura, Akane

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 691 KB

english, 2014

13

Analysis of JmjC Demethylase-Catalyzed Demethylation Using Geometrically-Constrained Lysine Analogues

Langley, Gareth W., Brinkø, Anne, Münzel, Martin, Walport, Louise J., Schofield, Christopher J., Hopkinson, Richard J.

Journal:

ACS Chemical Biology

Année:

2015

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2015

14

Is JmjC Oxygenase Catalysis Limited to Demethylation?

Hopkinson, Richard J., Walport, Louise J., Münzel, Martin, Rose, Nathan R., Smart, Tristan J., Kawamura, Akane, Claridge, Timothy D. W., Schofield, Christopher J.

Journal:

Angewandte Chemie

Année:

2013

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2013

15

Is JmjC Oxygenase Catalysis Limited to Demethylation?

Hopkinson, Richard J., Walport, Louise J., Münzel, Martin, Rose, Nathan R., Smart, Tristan J., Kawamura, Akane, Claridge, Timothy D. W., Schofield, Christopher J.

Journal:

Angewandte Chemie International Edition

Année:

2013

Langue:

english

Fichier:

PDF, 1.44 MB

english, 2013

16

ChemInform Abstract: The Ugi Four-Component Reaction Enables Expedient Synthesis and Comparison of Photoaffinity Probes.

Bush, Jacob T., Walport, Louise J., McGouran, Joanna F., Leung, Ivanhoe K. H., Berridge, Georgina, van Berkel, Sander S., Basak, Amit, Kessler, Benedikt M., Schofield, Christopher J.

Journal:

Année:

2014

Fichier:

PDF, 31 KB

2014

17

ChemInform Abstract: Total Synthesis of the Antitumor Antibiotic (.+-.)-Streptonigrin: First- and Second-Generation Routes for de Novo Pyridine Formation Using Ring-Closing Metathesis.

Donohoe, Timothy J., Jones, Christopher R., Kornahrens, Anne F., Barbosa, Luiz C. A., Walport, Louise J., Tatton, Matthew R., O'Hagan, Michael, Rathi, Akshat H., Baker, David B.

Journal:

Année:

2014

Fichier:

PDF, 19 KB

2014

18

Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases

Walport, Louise J., Hopkinson, Richard J., Chowdhury, Rasheduzzaman, Schiller, Rachel, Ge, Wei, Kawamura, Akane, Schofield, Christopher J.

Journal:

Nature Communications

Année:

2016

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2016

19

Exploring sequence space: harnessing chemical and biological diversity towards new peptide leads

Obexer, Richard, Walport, Louise J, Suga, Hiroaki

Journal:

Current Opinion in Chemical Biology

Année:

2017

Langue:

english

Fichier:

PDF, 2.25 MB

english, 2017

20

Highly selective inhibition of histone demethylases by de novo macrocyclic peptides

Kawamura, Akane, Münzel, Martin, Kojima, Tatsuya, Yapp, Clarence, Bhushan, Bhaskar, Goto, Yuki, Tumber, Anthony, Katoh, Takayuki, King, Oliver N. F., Passioura, Toby, Walport, Louise J., Hatch, Stepha

Journal:

Nature Communications

Année:

2017

Langue:

english

Fichier:

PDF, 1.69 MB

english, 2017

21

Strategies for transitioning macrocyclic peptides to cell-permeable drug leads

Walport, Louise J, Obexer, Richard, Suga, Hiroaki

Journal:

Current Opinion in Biotechnology

Année:

2017

Langue:

english

Fichier:

PDF, 2.12 MB

english, 2017

22

Human histone demethylase KDM6B can catalyse sequential oxidations

Hopkinson, Richard J., Langley, Gareth W., Belle, Roman, Walport, Louise J., Dunne, Kate, Münzel, Martin, Salah, Eidarus, Kawamura, Akane, Claridge, Timothy D. W., Schofield, Christopher J.

Journal:

Chemical Communications

Année:

2018

Langue:

english

Fichier:

PDF, 2.15 MB

english, 2018

23

Adventures in Defining Roles of Oxygenases in the Regulation of Protein Biosynthesis

Walport, Louise J., Schofield, Christopher J.

Journal:

The Chemical Record

Année:

2018

Langue:

english

Fichier:

PDF, 3.14 MB

english, 2018

24

Mechanistic and Structural Studies of KDM-Catalysed Demethylation of Histone 1 Isotype 4 at Lysine 26

Walport, Louise J, Hopkinson, Richard J, Chowdhury, Rasheduzzaman, Zhang, Yijia, Bonnici, Joanna, Schiller, Rachel, Kawamura, Akane, Schofield, Christopher J

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 905 KB

english, 2018

25

Hypoxia and hypoxia mimetics differentially modulate histone post-translational modifications

Hsu, Kuo-Feng, Wilkins, Sarah E., Hopkinson, Richard J., Sekirnik, Rok, Flashman, Emily, Kawamura, Akane, McCullagh, James S.O., Walport, Louise J., Schofield, Christopher J.

Journal:

Année:

2020

Fichier:

PDF, 8.52 MB

2020

26

Cyclic peptides can engage a single binding pocket through highly divergent modes

Patel, Karishma, Walport, Louise J., Walshe, James L., Solomon, Paul D., Low, Jason K. K., Tran, Daniel H., Mouradian, Kevork S., Silva, Ana P. G., Wilkinson-White, Lorna, Norman, Alexander, Franck, C

Journal:

Proceedings of the National Academy of Sciences

Année:

2020

Fichier:

PDF, 2.41 MB

2020